THESIS
2019
xvi, 102 pages : illustrations (some color) ; 30 cm
Abstract
3D cell culturing technologies are gaining momentum among research institutes and
pharmaceutical companies, since they can generate more physiologically relevant data
for better prediction and translation of results. Hydrogels, noted for their biomimetic
properties, are the leading materials for 3D cell culturing. Although a good number of
products have been established and commercialized for the cell culture purpose, few of
them enable facile recovery of cells after encapsulation under physiological conditions,
which thus presents great challenges for the long-term maintenance of 3D cell culture.
Here we present a proprietary recombinant protein hydrogel. This protein-based
photoresponsive hydrogel system enables not only 3D cell culture but also easy cell
release, thus holdin...[
Read more ]
3D cell culturing technologies are gaining momentum among research institutes and
pharmaceutical companies, since they can generate more physiologically relevant data
for better prediction and translation of results. Hydrogels, noted for their biomimetic
properties, are the leading materials for 3D cell culturing. Although a good number of
products have been established and commercialized for the cell culture purpose, few of
them enable facile recovery of cells after encapsulation under physiological conditions,
which thus presents great challenges for the long-term maintenance of 3D cell culture.
Here we present a proprietary recombinant protein hydrogel. This protein-based
photoresponsive hydrogel system enables not only 3D cell culture but also easy cell
release, thus holding great promise for applications like harmless cell transfer. This thesis
also describes the business proposal of a biotech startup, SPES Tech, founded with this core technology in hope of realizing the commercialization of this novel protein hydro gel
material.
Post a Comment