A multilevel antimicrobial coating with “release-killing”, “contact-killing” and “anti-adhesion” properties was prepared from polymer-encapsulated chlorine dioxide (ClO₂) using water-in-oil-in-water (w/o/w) double emulsion. The applied microencapsulation technology in this project made a stable double emulsion which protected the active ingredient from the outside environment, and they acted in a smart way to control the release rate at different temperatures. Meanwhile, the smart antimicrobial coating was proven to be safe under normal utilization.

Several kinds of anti-pathogen tests were conducted in this project; the results have proven that this double-layer emulsion antimicrobial coating provided a long term antimicrobial efficiency against tested microorganisms, such as...[ Read more ]

A multilevel antimicrobial coating with “release-killing”, “contact-killing” and “anti-adhesion” properties was prepared from polymer-encapsulated chlorine dioxide (ClO₂) using water-in-oil-in-water (w/o/w) double emulsion. The applied microencapsulation technology in this project made a stable double emulsion which protected the active ingredient from the outside environment, and they acted in a smart way to control the release rate at different temperatures. Meanwhile, the smart antimicrobial coating was proven to be safe under normal utilization.

Several kinds of anti-pathogen tests were conducted in this project; the results have proven that this double-layer emulsion antimicrobial coating provided a long term antimicrobial efficiency against tested microorganisms, such as S.aureus, E.coli, P.aeruginosa, B.subtilis and other infectious pathogens found in hospitals. Research on the antimicrobial mechanism found that it was correlated with oxidative damage by reactive oxygen species. Antimicrobial coating has also been proven useful for infection control of spore-forming bacteria and viruses (eg. H1N1). Finally, a field test in hospital was conducted to mimic the real application conditions and the antimicrobial results are encouraging. All results demonstrated that the designed coating has a broad application prospect for infectious disease control in public places.