THESIS
2015
xix, 125 pages : illustrations (some color) ; 30 cm
Abstract
Polymers are large molecules made of small building units called monomers. They have been
extensively used in biomedical science and engineering. In the past few years, many new
polymers have emerged to meet the requests for materials with better performances. However,
new challenges have also arisen due to the fast development of this subject under the
background of an increasing aging population.
As a PhD student with a major knowledge in materials science and engineering, my studies
in the past four years were basically focused on exploring polymers for new applications in
biomedical engineering, specifically for cancer diagnosis and heart regeneration, which
include both the development of new materials and new processing approaches for existing
materials.
In the f...[
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Polymers are large molecules made of small building units called monomers. They have been
extensively used in biomedical science and engineering. In the past few years, many new
polymers have emerged to meet the requests for materials with better performances. However,
new challenges have also arisen due to the fast development of this subject under the
background of an increasing aging population.
As a PhD student with a major knowledge in materials science and engineering, my studies
in the past four years were basically focused on exploring polymers for new applications in
biomedical engineering, specifically for cancer diagnosis and heart regeneration, which
include both the development of new materials and new processing approaches for existing
materials.
In the first part, I briefly review some applications of various polymers in biomedical
science and engineering, including basic study in cell biology, antimicrobial coating, cancer
diagnosis, drug delivery systems and tissue engineering.
In the rest parts, I present the research projects completed during my PhD study, which
contain a novel copolymer for the isolation of folate receptor-positive cancer cells, a simple
method to engineer freestanding biomimetic cardiac patches for heart regeneration and a
universal and facile approach to modifying proteins so that their solutions can rapidly form
hydrogel upon mixing with a cross-linker.
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