The new concept of biomedicine is opening new fields of research and, in this way, new applications such as new ways for drug administration. Drug delivery from nanomaterials, working as a carrier, presents several advantages in comparison with conventional medicines since it is possible to take the drug to the same part of the body where it is needed and at the precise dose, acting just in the zone to be treated and avoiding the side effects.

The development of novel materials, combining electrospinning and electrospray processes, gives the chance to obtain a wide range of materials with multiple functionalities. These materials can act as a carrier for drug delivery systems, loaded with different active ingredients, biocompatible and biodegradables, controlling the release of the dru...[ Read more ]

The new concept of biomedicine is opening new fields of research and, in this way, new applications such as new ways for drug administration. Drug delivery from nanomaterials, working as a carrier, presents several advantages in comparison with conventional medicines since it is possible to take the drug to the same part of the body where it is needed and at the precise dose, acting just in the zone to be treated and avoiding the side effects.

The development of novel materials, combining electrospinning and electrospray processes, gives the chance to obtain a wide range of materials with multiple functionalities. These materials can act as a carrier for drug delivery systems, loaded with different active ingredients, biocompatible and biodegradables, controlling the release of the drug over time and improving the healing process. Furthermore, due to the nanofiber and nanoparticle morphology, the materials can also be used in air filtration techniques, capturing particles and disinfecting the environment, thanks to their antimicrobial properties.

A novel and versatile X-Y-X electrospinning equipment was designed and started up properly. The equipment's precision and effectiveness were proved by synthesizing nano and micro-structures in near-field studies. Furthermore, the control on the diameter size of the nanofibers was shown by changing the operating parameters working on the far-field.

The design of several materials with functional properties was suitably obtained, combining some of them, the electrospray and electrospinning technique, and giving better antibacterial and filtering properties. The synthesis of composite nanofibers, covering the surface of the fibres with MOF materials, proved their efficacy in being used as a carrier for different drugs. The release of active ingredients over time was suitable and linear in most cases, being all biocompatible and great candidates for biomedical applications.